KMID : 0369820070370010023
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Jorunal of Korean Pharmaceutical Sciences 2007 Volume.37 No. 1 p.23 ~ p.26
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Crystal Form of Cefuroxime axetil
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Sohn Young-Teak
Kim Bo-Yeon
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Abstract
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Two cry stal forms of cefuroxime axetil were obtained by the recrystallization from different organic solvents and characterized by differential scanning calorimetry ( DSC), X-ray powder diffraction (XRD), It was confirmed that two crystal forms are identical. The dissolution patterns of these two forms were also checked in 0.07N HCl at 37 ¡¾ 0.5¡É, 100 rpm for 180 minutes. The transformation during storage was also studied.
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KEYWORD
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cefuroxime axetil, crystal form, Transformation, DSC, XRD
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