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KMID : 0369820070370010023
Jorunal of Korean Pharmaceutical Sciences
2007 Volume.37 No. 1 p.23 ~ p.26
Crystal Form of Cefuroxime axetil
Sohn Young-Teak

Kim Bo-Yeon
Abstract
Two cry stal forms of cefuroxime axetil were obtained by the recrystallization from different organic solvents and characterized by differential scanning calorimetry ( DSC), X-ray powder diffraction (XRD), It was confirmed that two crystal forms are identical. The dissolution patterns of these two forms were also checked in 0.07N HCl at 37 ¡¾ 0.5¡É, 100 rpm for 180 minutes. The transformation during storage was also studied.
KEYWORD
cefuroxime axetil, crystal form, Transformation, DSC, XRD
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